Shephard's Purse

by jockques cliatt

Shephard's Purse is a lowkey super herb, but its real super power is how it rids the body of unwanted inflammation due to chronic illness like type 2 diabetes, obesity, the elderly, vascular disease, chronic renal failure, and several cancers


Shepherd's purse (Capsella bursa-pastoris (L.) Medik.), a wild herb (Figure 1) with high nutritional value and has been eaten raw or cooked as a vegetable for thousands of years in many countries, is getting more and more attention. Shepherd's purse has been used as traditional herbal medicine for a long history which has been recorded in TCM ancient books “Ben Cao Gang Mu,” “Ming Yi Bie Lu,” and so on. Previous studies found that shepherd's purse contained a wide range of chemicals including flavonoids, alkaloids, polypeptides, choline, acetylcholine, histamine, tyramine, fatty acids, sterols, organic acids, amino acids, sulforaphane, many trace elements, vitamins, and many other compounds. Furthermore, pharmacological studies also proved that shepherd's purse with various bioactivities, including anti-inflammatory, antioxidative, antiallergic, AChE inhibitory activity, and anticancer effects in previous studies. Choi et al. prepared a sulforaphane-containing solution component from shepherd's purse and found it had significant anti-inflammatory activity. Lan et al. found that the EtOAc extract of Capsella bursa-pastoris which with apigenin-7-O-β-D-glucopyranoside, luteolin-7-O-β-D glucopyranoside, α-adenosine, and uridine showed stronger anti-inflammatory activities in carrageenan-induced paw edema experiment and egg-albumin-induced inflammation experiment . Even though little studies found shepherd's purse with anti-inflammatory activity, the chemical composition, antioxidative and anti-inflammatory activities of the extract of shepherd's purse, and its underlying mechanisms have not been systematically studied. Therefore, the aim of the present study was to systematically investigate the chemical composition, anti-oxidative and anti-inflammatory activities of shepherd's purse extract, and their underlying mechanisms using LPS-induced RAW 264.7 cells and an in vivo carrageenan-induced mouse paw edema model